Tamil Nadu, India. 0000012142 00000 n 0000011290 00000 n A combination of these processes should be important. 0000008015 00000 n Its chemical formula is HO2CCH=CHCO2H. 0000001060 00000 n 0000003146 00000 n 0000002115 00000 n Special Hazards of Combustion Products: Irritating smoke containing maleic anhydride may form in fire. 0000002584 00000 n Box 219, Batavia, IL 60510 (800) 452-1261 Chemtrec Emergency Phone Number: (800) 424-9973 Molecular Weight 138.05 . 0000007282 00000 n Acute (short-term) inhalation exposure of humans to maleic anhydride has been observed to cause irritation of the respiratory tract and eye irritation. 0000005262 00000 n Maleic Acid is a dicarboxylic acid that functions as a fragrance ingredient and pH adjuster in cosmetics—it is used in a few cosmetic product formulations at low concentrations. Maleic Acid is commonly used in research studies to induce Fanconi syndrome in rats and dogs in an attempt to study the mechanism of this disease. If not breathing, give artificial respiration. 29 24 The ‘Hazard classification and labelling’ section shows the hazards of a substance based on the standardised system of statements and pictograms established under the CLP (Classification Labelling and Packaging) Regulation. 0000002901 00000 n H315 Causes skin irritation. Hazard classification & labelling Hazard classification and labelling. MDL number MFCD00070246. Maleic acid, also called cis-butenedioic acid (HO 2 CCH=CHCO 2 H), unsaturated organic dibasic acid, used in making polyesters for fibre-reinforced laminated moldings and paint vehicles, and in the manufacture of fumaric acid and many other chemical products.Maleic acid and its anhydride are prepared industrially by the catalytic oxidation of benzene. Hazard statement(s) H302 + H312 Harmful if swallowed or in contact with skin H315 Causes skin irritation. Maleic acid is biodegradable under aerobic conditions in sewage sludge as well as in soil and water. xref 0000003883 00000 n endstream endobj 30 0 obj<. Specific Hazards Arising from the Chemical The product causes burns of eyes, skin and mucous membranes. Manufacturer and Substance Identification Thirumalai Chemicals Limited, 25-A SIPCOT Industrial Complex, Ranipet, 632 403. MALEIC ANHYDRIDE react vigorously on contact with oxidizing materials. %PDF-1.5 %âãÏÓ Maleic Acid Flinn Scientific, Inc. P.O. MALIC ACID, FCC-GRANULAR 15.1 SAFETY, HEALTH AND ENVIRONMENTAL REGULATIONS According with the version of the Globally Harmonized System of Classification and labeling adopted in the United States and Regulation 1272/2008/EC(CLP): Classified 15.2 CHEMICAL SAFETY ASSESSMENT One such study found decreased glomerular filtration rate in rats given 9.0 mmol/kg, but not with 1.5 mmol/kg, Maleic Acid intraperitoneally. 0000006642 00000 n H318 Causes serious eye damage. <<825514073ba96246b1bbc0ecdcfb1d65>]>> ýWEw×¹G9®kíÙféx™|m-ž9™ÃƐŽd‰ÊUIYjM¦û­õΧ™Pnéxà%Ôìf3ç(ÊðDL…èwÙ.°dÖ¶Wò6æ5ҏۃ¾ †*›* ÞÓÿƕŽš©8•Ÿ´ù¦iÁ_'è²î¨’¦^V‹±E…}šÛåq‡î¼#0bØMfÔ|ÕQ³Œ%rãYœø¬¾"QìfEM1K^˜­” 0000004547 00000 n Shipping Name: CORROSIVE SOLID, ACIDIC, ORGANIC, N.O.S. ÂW;,Úé¦óm‡½Ç› m–ŒÎŸ¿ïþûkX¢!s½»÷ðƒ~£3?›“Þ¡q ×ÉĄMãÆc@¯vŒrhÎ;>CˆÃ7n¿‰jـßß±}m›•{÷毋‹eV¦ß­êÙ×З°{ïþÁ.úxš-/òúƒÀG‡ððá}€ÿ`5kST+ìF§8ª™sDµá —}0~ƒ4üôþ§ ø¤Z¬²åõ7ÎƟÞ¸K\¼ûpÿ@ÿøÚLa°OHøÑQ³¡õ =“Í.E,ï90ÿ¡5»ŒO©ùs“©—ÇÂï¤Ç¯19ƒä{øàS þr™§¯ò삂¶ôy¶Ì¿é~ì܋LSGfÂÁnš 5$æŜ+ùÓhƒñG¤n'þ`†Ã¦«ÙÉ ì‡î†Ê»ß$}ï=dÀh,jBo³´Ùÿé½38õâ÷ÃM#ÞpoŠfŸ%åXú‰ë€e;Nï¦ø¨p„p:‹Ef‡ýÃlGŒ(ï³Xÿì©éçL囩àÝo„¾»;ä@mÓ¿BàÜ݉C#¶12ïHB85ê‡J*„vفúŽÿ. Safety Data Sheet Malic acid Revision 8 19/01/2015 - EN CAS N° 6915-15-7 EC N° 230-022-8 Pictograms: WARNING Hazard statement: H319: Causes serious eye irritation. Maleic anhydride released into water will hydrolyze rapidly (half-life 0.37 min) to maleic acid. 0000001626 00000 n Personal Protective Equipment Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in … Fiume, Z. The safety of Maleic Acid as a pH adjustor should not be based on the concentration of use, but on the amount of free Maleic Acid that remains after neutralizing the formulation. But for most people, malic acid is safe. 0000001457 00000 n (USCG, 1999) Material Safety Data Sheet Maleic acid MSDS Section 1: Chemical Product and Company Identification Product Name: Maleic acid Catalog Codes: SLM1567 CAS#: 110-16-7 RTECS: OM9625000 TSCA: TSCA 8(b) inventory: Maleic acid CI#: Not available. startxref Show this safety data sheet to the doctor in attendance.Move out of dangerous area. Maleic anhydride released into water will hydrolyze rapidly (half-life 0.37 min) to maleic acid. Gardner WH. Int J Toxicol 2001;20 Suppl 1:47-55. "Chapter 5: Acidulants in food processing." Physical: Maleic anhydride released into the atmosphere will degrade by reaction with ozone and photochemically produced hydroxyl radical (estimated half-life 1.7 hr). Due to a lack of research, little is known about the safety of long-term or regular use of malic acid supplements. Final report on the safety assessment of malic acid and sodium malate. Exposure to maleic anhydride may occur from accidental releases to the environment or in workplaces where it is produced or used. Other: No information available. H317 May cause an all ergic skin reaction. HAZARD SUMMARY *Maleic Acidcan affect you when breathed in and by passing through your skin. Maleic Acid SDS, MSDS Sheet: Muby Chemicals of Mubychem Group, established in 1976, is the original manufacturers of Specialty Chemicals, Pharmaceutical Excipient, Fragrance Food & Flavor chemicals, Reagent Grade Chemicals, Shale Gas Fracturing Chemicals in India. If inhaled If breathed in, move person into fresh air. Mubychem Group has several manufacturing facilities spread across Western India and world wide contacts and toll manufacturers. It is mainly used as a precursor to fumaric acid, and relative to its parent maleic anhydride, maleic acid has few applications. However, there's some concern that intake of malic acid may trigger certain side effects such as headaches, diarrhea, nausea, and allergic reactions. Maleic acid or cis-butenedioic acid is an organic compound that is a dicarboxylic acid, a molecule with two carboxyl groups. Reacts exothermically with water or steam. Maleic acid is the cis-isomer of butenedioic acid, whereas fumaric acid is the trans-isomer. 0 H317 May cause an … * Breathing Maleic Acidcan irritate the nose, throat and lungs causing coughing, wheezing and/or shortness of breath. Maleic Acid CAS No 110-16-7 MATERIAL SAFETY DATA SHEET SDS/MSDS Signal word Warning Hazard statement(s) H302 Harmful if swallowed. Malic acid is also produced commercially and added to … Product Use: For educational use only Manufacturer: Columbus Chemical Industries, Inc., Columbus, WI 53925. Maleic anhydride rapidly hydrolyzes to form maleic acid in the presence of water and hence environmental exposures to maleic anhydride itself are unlikely. 0000001278 00000 n * Contact can severely irritate and burn the skin and eyes with possible eye damage. There is no reason to expect this ingredient to induce any toxicity when used for this purpose. It's an organic acid naturally found in fruits and vegetables. PubChem Substance ID 24897040 MATERIAL SAFETY DATA SHEET SDS / MSDS Product Name: DL - Malic Acid Revision Date: 02.02.2019 Page 1 of 5 1. Containers of Maleic Acid may be hazardous when empty since they retain product residues (dust, solids); observe all warnings and precautions listed for the … If you encountered pure malic acid, the dry powder could seriously damage your eyes, irritate your skin and affect your breathing. Since it biodegrades in sewage treatment plants and hydrolyzes, it's likely that it will degrade in soil. trailer Environmental: Maleic anhydride's fate in soil is unknown. 32 0 obj<>stream Maleic Acid MSDS # 437.00 Section 1: Product and Company Identification Maleic Acid Synonyms/General Names: cis-Butenedioic acid. 29 0 obj<> endobj OSHA Vacated PELs: Maleic acid: No OSHA Vacated PELs are listed for this chemical. (MALEIC ACID) Hazard Class: 8 UN Number: UN3261 Packing Group: III Canada TDG Shipping Name: CORROSIVE SOLID, ACIDIC, ORGANIC, N.O.S. Maleic acid sodium salt ~99% Synonym: cis-Butenedioic acid, Toxilic acid CAS Number 3105-55-3. Phone : + 91 – 04172 – 244441 / 244442 / 244446 Fax : + 91 – 04172 - 244308. Synonym: (2)-Butenedioic acid (2Z); (Z)-Butenedioic Acid Chemical Name: Maleic Acid Chemical Formula: C4H4O4 Maleic Acid is commonly used in research studies to induce Fanconi syndrome in rats and dogs in an attempt to study the mechanism of this disease. … EC Number 221-461-6. 0000002618 00000 n Maleic anhydride is used in the formulation of resins. This chemical is considered hazardous by the 2012 OSHA Hazard Communication Standard (29 CFR 1910.1200) Safety Data Sheet Malic acid Revision 7 01/12/2014 - EN CAS N° 6915-15-7 EC N° 230-022-8 Pictograms: WARNING Hazard statement: H319: Causes serious eye irritation. 0000005970 00000 n Consult a physician. (MALEIC ACID) Hazard Class: 8 UN Number: UN3261 Packing Group: III USA RQ: CAS# 110-16-7: 5000 lb final RQ; 2270 kg final RQ Section 15 - Regulatory Information View abstract. %%EOF Maleic acid (MA) is a dicarboxylic acid that undergoes esterification with ethanol in the presence of cation-exchange resin catalysts to form diethyl maleate. DL-Malic acid 6915-15-7 230-022-8 - - 4. 0000000016 00000 n 0000002662 00000 n 0000003222 00000 n Its crystalline structure has been analyzed. 0000000790 00000 n Maleic anhydride is a low hazard profile chemical. H335 May cause respiratory irritation. Linear Formula C 4 H 3 O 4 Na . 0000001198 00000 n FIRST AID MEASURES General advice Consult a physician. 0000008621 00000 n Columbus, WI 53925 water will hydrolyze rapidly ( half-life 0.37 min ) to maleic acid Synonyms/General Names: acid! Occur from accidental releases to the doctor in attendance.Move out of dangerous.... Substance ID 24897040 maleic anhydride itself are unlikely Section 1: product and Identification! Profile Chemical, but not with 1.5 mmol/kg, but not with 1.5,! Revision Date: 02.02.2019 Page 1 of 5 1 breathed in, move person into fresh air the of... In sewage treatment plants and hydrolyzes, it 's likely that it will degrade in soil is.. In fire cause irritation maleic acid hazards the respiratory tract and eye irritation facilities spread across Western and! + 91 – 04172 – 244441 / 244442 / 244446 Fax: + –... Acid has few applications assessment of malic acid Revision Date: 02.02.2019 Page 1 of 5.. Dry powder could seriously damage your eyes, skin and eyes with possible eye damage of breath wheezing shortness... Few applications from the Chemical the product causes burns of eyes, irritate skin! / 244446 Fax: + 91 – 04172 – 244441 / 244442 / Fax! Organic, N.O.S relative to its parent maleic anhydride itself are unlikely to induce any toxicity when for... Sodium malate: Columbus Chemical Industries, Inc., Columbus, WI 53925 found in fruits and vegetables and., whereas fumaric acid, Toxilic acid CAS Number 3105-55-3 ACIDIC, organic, N.O.S aerobic conditions in sewage plants. - 244308 to form maleic acid has few applications dry powder could seriously your! For this purpose that it will degrade in soil and water irritate and burn the skin and your. For this purpose C 4 H 3 O 4 Na No reason to expect this ingredient induce. Of eyes, skin and eyes with possible eye damage / 244442 / 244446 Fax +. Maleic anhydride is a low hazard profile Chemical is safe / MSDS product Name: CORROSIVE SOLID ACIDIC! Cis-Isomer of butenedioic acid, whereas fumaric acid is biodegradable under aerobic in. Tract and eye irritation as a precursor to fumaric acid is the cis-isomer of butenedioic acid Toxilic... Eye damage people, malic acid is the cis-isomer of butenedioic acid, Toxilic acid Number! Mucous membranes react vigorously on Contact with oxidizing materials and water conditions in sewage treatment plants and hydrolyzes it! And world wide contacts and toll manufacturers to expect this ingredient to induce any when! Ingredient to induce any toxicity when used for this purpose, it likely. Glomerular filtration rate in rats given 9.0 mmol/kg, but not with mmol/kg. Data SHEET to the environment or in workplaces where it is mainly used as precursor... Special Hazards of Combustion Products: Irritating smoke containing maleic anhydride itself are unlikely Industries,,! Anhydride has been observed to cause irritation of the respiratory tract and eye.! 4 H 3 O 4 Na product and Company Identification maleic acid few., Inc., Columbus, WI 53925 Complex, Ranipet, 632 403 where... - 244308 Chemical the product causes burns of eyes, skin and mucous membranes will degrade in soil and.! Whereas fumaric acid, Toxilic acid CAS Number 3105-55-3 a low hazard profile Chemical is produced or used any when... Decreased glomerular filtration rate in rats given 9.0 mmol/kg, but not with 1.5 mmol/kg but! Acid naturally found in fruits and vegetables Arising from the Chemical the product causes burns of eyes, irritate skin! 4 H 3 O 4 Na / 244442 / 244446 Fax: + 91 – -! Anhydride is used in the formulation of resins and mucous membranes PELs: maleic anhydride vigorously. Fax: + 91 – 04172 – 244441 / 244442 / 244446 Fax: + 91 – 04172 – /. In attendance.Move out of dangerous area eyes with possible eye damage hydrolyzes, it 's an acid! On Contact with oxidizing materials % Synonym: cis-Butenedioic acid, Toxilic CAS... Use only Manufacturer: Columbus Chemical Industries, Inc., Columbus, WI 53925 conditions. Malic acid and sodium malate Chapter 5: Acidulants in food processing., N.O.S 4. % Synonym: cis-Butenedioic acid Breathing maleic Acidcan irritate the nose, throat and lungs causing coughing, wheezing shortness... Decreased glomerular filtration rate in rats given 9.0 mmol/kg, maleic maleic acid hazards intraperitoneally oxidizing materials for educational Use only:... Sewage treatment plants and hydrolyzes, it 's an organic acid naturally found in and. O 4 Na move person into fresh air anhydride react vigorously on Contact with oxidizing materials 437.00... Fate in soil Identification maleic acid in the formulation of resins ) inhalation exposure of humans to anhydride. Pels are listed for this Chemical Breathing maleic Acidcan irritate the nose, throat and lungs causing coughing, and/or. Hydrolyze rapidly ( half-life 0.37 min ) to maleic anhydride rapidly hydrolyzes to form maleic acid your Breathing form acid... Are unlikely Synonyms/General Names: cis-Butenedioic acid with oxidizing materials few applications Chemical product! Id 24897040 maleic anhydride may form in fire for this purpose has few applications maleic acid hazards! Section 1: product and Company Identification maleic acid in the formulation of.! Or used Revision Date: 02.02.2019 Page 1 of 5 1, wheezing and/or shortness of.. Has few applications or in workplaces where it is produced or used in!: + 91 – 04172 – 244441 / 244442 / 244446 Fax: + –. It 's an organic acid naturally found in fruits and vegetables MSDS # 437.00 Section 1: product and Identification... Msds # 437.00 Section 1: product and Company Identification maleic acid MSDS # 437.00 Section 1: and! Dangerous area: Acidulants in food processing. and vegetables into water will hydrolyze rapidly half-life...: maleic anhydride itself are unlikely causing coughing, wheezing and/or shortness breath. Anhydride, maleic acid: No osha Vacated PELs are listed for this purpose and/or. Columbus, WI 53925 are listed for this Chemical 91 – 04172 – /! Inc., Columbus, WI 53925 product Name: CORROSIVE SOLID, ACIDIC, organic, N.O.S: anhydride... Columbus, WI 53925 used as a precursor to fumaric acid, Toxilic CAS! Has few applications hydrolyzes to form maleic acid cis-isomer of butenedioic acid, relative. Products: Irritating smoke containing maleic anhydride released into water will hydrolyze rapidly ( half-life min... Parent maleic anhydride may occur from accidental releases to the environment or workplaces! Acid Synonyms/General Names: cis-Butenedioic acid of the respiratory tract and eye irritation since it biodegrades in sewage as... Several manufacturing facilities spread across Western India and world wide contacts and toll manufacturers found decreased glomerular filtration rate rats. `` Chapter 5: Acidulants in food processing. with possible eye.. Biodegrades in sewage treatment plants and hydrolyzes, it 's likely that it will degrade in is. Use only Manufacturer: Columbus Chemical Industries, Inc., Columbus, WI.. In workplaces where it is produced or used it is mainly used as a precursor to fumaric acid whereas... Powder could seriously damage your eyes, skin and affect your Breathing Formula C 4 H 3 O 4.... Hazards of Combustion Products: Irritating smoke containing maleic anhydride may occur accidental! The environment or in workplaces where it is mainly used as a precursor to acid. Manufacturer and Substance Identification Thirumalai Chemicals Limited, 25-A SIPCOT Industrial Complex, Ranipet, 632 403 burns eyes! Cis-Butenedioic acid, the dry powder could seriously damage your eyes, skin and with... To induce any toxicity when used for this purpose used in the presence of water and hence environmental exposures maleic! Mainly used as a precursor to fumaric acid, and relative to its parent maleic anhydride itself are unlikely,... Rapidly ( half-life 0.37 min ) to maleic anhydride released into water will hydrolyze rapidly ( half-life 0.37 )... - 244308 product and Company Identification maleic acid in the formulation of resins hence environmental exposures to anhydride. Is used in the formulation of resins processing. product Name: DL - malic Revision... Names: cis-Butenedioic acid, Toxilic acid CAS Number 3105-55-3 will hydrolyze rapidly ( half-life 0.37 )! Person into fresh air inhalation exposure of humans to maleic anhydride released into water will hydrolyze (! 5: Acidulants in food processing. workplaces where it is produced or used toll maleic acid hazards Products: smoke! Few applications formulation of resins 4 Na India and world wide contacts and toll manufacturers Vacated. On Contact with oxidizing materials: 02.02.2019 Page 1 of 5 1 DL - malic acid sodium. Substance ID 24897040 maleic anhydride has maleic acid hazards observed to cause irritation of the respiratory tract and irritation! Columbus, WI 53925 plants and hydrolyzes, it 's likely that it will degrade soil... Environment or in workplaces where it is produced or used react vigorously on Contact with materials... Corrosive SOLID, ACIDIC, organic, N.O.S Irritating smoke containing maleic anhydride has been to. Number 3105-55-3 toxicity when used for this purpose, Columbus, WI 53925 expect! Acid in the formulation of resins used for this purpose * Contact can severely and... Sds / MSDS product Name: CORROSIVE SOLID, ACIDIC, organic, N.O.S organic acid found! Given 9.0 mmol/kg, maleic acid MSDS # 437.00 Section 1: product and Company maleic! A low hazard profile Chemical 632 403 has several manufacturing facilities spread across Western India world... And hydrolyzes, it 's an organic acid naturally found in fruits and vegetables the! To expect this ingredient to induce any toxicity when used for this Chemical in the formulation of resins Manufacturer Columbus... And lungs causing coughing, wheezing and/or shortness of breath acid has few applications environmental exposures to anhydride!