Plasma membrane channels formed by connexins: their regulation and functions. Lycopene is not only found in the skin but is irregularly distributed in other tissues of the body, such as testes, adrenals, prostate, liver, breast, pancreas, kidney, lungs, colon, ovary and stomach6. More information at www.ConsumerLab.com/survey. Accessed May 25, 2012. The antioxidant properties help balance free radical activity in the body and in doing so, may offer protection against certain diseases, keep bones strong and healthy, and help eyesight by helping delay or prevent cataracts, macular degeneration, and other age-rela… Other Potential Benefits DMAE can be consumed orally (KRS products are intended for topical, external use only, not internal), or you can apply it directly to the skin to benefit from its skin enhancing benefits. Lycopene may help increase your skin’s defense against sunburns and damage caused by UV rays. Grapefruit also has unique phytochemicals (a.k.a. New research on lycopene, a unique carotenoid, has shown it has an ability to defend against some of the factors of skin aging. DMAE helps to tighten skin and reduce sagging, improve firmness and elasticity, smooth lines and wrinkles, and brighten the skin. Skin lycopene is more sensitive to ultraviolet radiation and is degraded faster than beta-carotene, suggesting its photoprotective role2. 2002 Nov;227(10):845-51. The powerful antioxidant properties of lycopene fight free radicals and oxidative stress. Chen P, Zhang W, Wang X, Zhao K, Negi DS, Zhuo L, Qi M, Wang X, Zhang X. Lycopene and Risk of Prostate Cancer: A Systematic Review and Meta-Analysis. 2. 1. In fact, a study conducted by the Department of Dermatology at the Mount Sinai School of Medicine, examined topically-applied lycopene's ability to defend against the harmful effects of UVB radiation. Di Mascio P, Kaiser S, Sies H. Lycopene as the most efficient biological carotenoid singlet oxygen quencher. Khachik F, Carvalho L, Bernstein PS, Muir GJ, Zhao DY, Katz NB. The topical application of lycopene was found to reverse the reduction of PCNA caused by UVB exposure to a significant degree. Besides protecting your skin cells from free radical damage and enhancing certain aspects of cell metabolism, lycopene also appears to produce its beneficial effects by improving the operation of cell-to-cell junctions.11 Also known as gap junctions, they coordinate cellular behavior by directly connecting the cytoplasm of two cells so that molecules and ions can pass freely between them.12,13 Gap junction communication can be found in all the different tissues of your body, with skeletal muscle and mobile cell types like sperm or red blood cells being the only exceptions.13 Gap junctions are particularly important to your skin because it is highly dependent upon intercellular communication for vital metabolic processes related to growth and reproduction. Some people claim the enzymes in tomatoes can offer exfoliation benefits when applied to the skin. 2010;164(1):154–162. Aust O, Ale-Agha N, Zhang L, Wollersen H, Sies H, Stahl W. Lycopene oxidation product enhances gap junctional communication. 5. American Journal of Clinical Nutrition. Lycopene Benefits & Skin Health. Lycopene's antioxidant and UV-blocking capabilities naturally make it a valuable weapon in the battle against aging skin.2,3, Some of the fruits and vegetables rich in lycopene include pink grapefruit, papaya, wolfberry, goji, and tomatoes. Carotenoids and human health. Lycopene Crema Rinnovante The number #1 antioxidant - lycopene, along with Corylus Avellana rich in vitamin E, Calendula Officinalis contains vitamin A, Centelle Asiatica promotes collagen production, Salvia Officinalis has antibacterial and antiseptic properties, and 14 other natural botanicals. Tomatoes. 2005; 135(3):592-7. 9. †2020 Consumer Satisfaction, Rated #1 Catalog/Internet Merchant. Other potential anticancer effects of lycopene are observed in lung cancer, breast cancer, colorectal cancer, gastric cancer, pancreatic cancer and ovarian cancer8-13. 7. Oregon State University found that both dietary and topical use of vitamin C … 2003 Oct;83(4):1359-400. 5. Lycopene may also strengthen your skin by inhibiting the activity of enzymes involved in the destruction and breakdown of collagen. Critical Reviews in Food Science and Nutrition. Lycopene content of tomatoes and tomato products. 2008;42(1):94-102. It does not cause sunburn but does age the skin; UV-B causes reddening and pain and is responsible for the majority of sunburns; Food Science and Nutrition. Topical use of vitamin K may also treat rosacea, a chronic, inflammatory skin condition characterized by redness and pimples on the face. Crit Rev Food Sci Nutr. 2018;9:521. 2019;7(4):1157-1165. Theoretically, lycopene's ability to regulate cell-to-cell junctions might provide an additional benefit of improving skin texture. Studies indicate that topically applied lycopene defends against skin aging by helping to stabilize DNA structure in the nucleus of skin cells, enhancing skin-cell signaling and function, and inhibiting enzymatic activity involved in collagen breakdown. Rao AV, Rao LG. Lycopene, the red pigment that gives tomatoes their color, is the most studied and potent of all of the antioxidants. In addition, it was shown that lycopene may also protect your skin through its ability to reduce inflammation, encourage cell renewal, and inhibit normal DNA damage following UVB injury.9. If you have any questions on the scientific content of this article, please call a Life Extension® Health Advisor at 1-866-864-3027. This salt may also be used for purposes not listed in this medication guide. They combat inflammation, thereby preventing serious ailments like cancer and heart disease. So, you will have younger-looking skin for years. Li Y, Zhang J. Serum concentrations of antioxidant vitamins and carotenoids are low in individuals with a history of attempted suicide. All Contents Copyright ©2021 Life Extension, Request FREE issue of Life Extension Magazine®, Website & Technology Accessibility Statement, An error on our end has caused the item you were trying to add to your cart to fail, please try again or call, Chemistry Panel & Complete Blood Count (CBC), http://www.smartskincare.com/treatments/topical/lycopene.html, http://www.tandfonline.com/doi/abs/10.1207/s15327914nc4702_11#preview, Topical Lycopene Improves Skin Cellular Function. Vrieling A, Voskuil DW, Bonfrer JM, Korse CM, van Doorn J, Cats A, Depla AC, Timmer R, Witteman BJ, van Leeuwen FE, Van’t Veer LJ, Rookus MA, Kampman E. Lycopene supplementation elevates circulating insulin-like growth factor binding protein-1 and -2 concentrations in persons at greater risk of colorectal cancer. British Journal of Dermatology. Molecular Nutrition and Food Research. Lycopene and Vascular Health. The antioxidant (free radical scavenging) activity of lycopene exceeds that of gamma-carotene, astaxanthin, alpha-carotene, beta-carotene, zeaxanthin and lutein; it is also 100 times more powerful than alpha-tocopherol5. A meta-analysis of 26 studies with 563,299 participants indicated an association of a lower risk of prostate cancer with higher lycopene supplementation and circulating concentrations7. Lycopene-rich treatments modify noneosinophilic airway inflammation in asthma: proof of concept. Han GM, Meza JL, Soliman GA, Islam KM, Watanabe-Galloway S. Higher levels of serum lycopene are associated with reduced mortality in individuals with metabolic syndrome. J Nutr Biochem. 1999;19(2):305–323. Lycopene Topical is used for Light induced skin damage and other conditions. Dietary intake of lycopene is associated with reduced pancreatic cancer risk. Nutrition Research. 4. Studies indicate that topically applied lycopene defends against skin aging by helping to stabilize DNA structure in the nucleus of skin cells, enhancing skin-cell signaling and function, and inhibiting enzymatic activity involved in collagen breakdown. Lycopene belongs to a general group of more than 600 fat-soluble plant compounds known as carotenoids. Saw Palmetto. A unique combination of pharmacological functions of Pycnogenol® provides an unmatched variety of health benefits for skin health. Accessed May 25, 2012. It also boasts essential phytonutrients -- such as lycopene, beta-carotene and bioflavonoids -- that promote cellular health. The ability of lycopene to block UV light is an additional benefit for the skin. Rizwan M, Rodriguez-Blanco I, Harbottle A, Birch-Machin MA, Watson REB, Rhodes LE. Alda LM, Gogoasa I, Bordean DM, et al. Squalene and lycopene reduce sagginess, improve elasticity and lift and firm the skin. 1995;125(7):1854–1859. Pycnogenol® French maritime pine bark extract is widely used in topical and oral applications for various dermatological indications. Lycopene benefits the skin by helping it resist ultraviolet rays. New research on lycopene, a unique carotenoid, has shown it has an ability to defend against some of the factors of skin aging. Benefits of Lycopene for Skin and Health. Recently, the Department of Dermatology at the Mount Sinai School of Medicine investigated the protective effects of topically applied lycopene against the photodamage seen in skin exposed to ultraviolet (UVB)-irradiation; the radiation that is responsible for sunburn. Our products are infused with micro-dispersed aquose Lycopene, which is the #1 antioxidant recommended by Doctors. Lifestyle modification of the masses towards healthy foods has led to increased dietary intake of lycopene that directly coincides with the presence of lycopene in the skin. Topical application of lycopene combats age-causing free radicals and assists in metabolic functions related to growth and repair. 2016;36(5):402-7. Holick CN, Michaud DS, Stolzenberg-Solomon R, Mayne ST, Pietinen P, Taylor PR, Virtamo J, Albanes D. Dietary carotenoids, serum beta-carotene, and retinol and risk of lung cancer in the alpha-tocopherol, beta-carotene cohort study. Lycopene can benefit any skin type, but works especially well for sensitive and aging skin. Topical Lycopene Improves Skin Cellular Function. Nkondjock A, Ghadirian P, Johnson KC, Krewski D, Canadian Cancer Registries Epidemiology Research Group. bioflavanoids) that help promote skin health and general health. 13. 2007;5(4):327-36. It may help improve the health and appearance of your skin. Cancer Epidemiology, Biomarkers and Prevention. Protective effect of total carotenoid and lycopene intake on the risk of hip fracture: a 17-year follow-up from the Framingham Osteoporosis Study. Lycopene health benefits include treating neurological disorder, preventing stroke, supporting immune system, preventing macular degeneration, alleviating osteoporosis, fighting diabetes, treating prostate cancer, controlling cholesterol level, treating infertility, promoting hair growth, treating scalp diseases, and slowing down aging process. Grapefruit is rich in natural ingredients that nourish and protect the skin, including vitamins A, C and E and antioxidants. 10. American Journal of Epidemiology. One of the biggest benefits of lycopene is that it is an antioxidant and protects the body of damage from free radical stress, which can hurt DNA and other cell structures. Let food be your medicine: nutraceutical properties of lycopene. 2002; 156(6):536-47. Nutritional Neuroscience. 1989;274(2):532–538. In one study, postmenopausal supplementation with lycopene showed reduced oxidative stress parameters as well as the bone resorption marker N-telopeptide of Type I collagen (NTx) which is linked to osteoporosis. The 5 Main Benefits of Antioxidants for Your Skin Antioxidants help correct signs of age. Also, the antioxidant calms the body's inflammatory process, reducing redness and irritation, according to … 2009;24(6):1086-94. The same study also revealed that UVB radiation depleted an important substance in your skin known as PCNA (proliferating cell nuclear antigen), which is vital for DNA synthesis and cell repair. Essential phytonutrients -- such as lycopene, which is the most common dietary sources of lycopene age-causing. To burns, blistering, sun damage, and ketchup.2 boasts essential phytonutrients such. 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